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Specifically, Mitchell and Janzen (2010) modeled that the genetic variation of reptiles with TSD may not be sufficient to cope with high rates of climate change, highlighting the limits of their potential adaptive capacity ( These assessments highlight that the potential for genetic adaptation is limited not only by the size of the gene pool but also by the speed at which that gene pool responds to selection

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60.1%) and younger (mean age, 45.9 years vs

doi: 10.1177/096032719101000506

This causes a rise in lipid peroxidation, which triggers the death of hair cells, supporting cells, stria vascularis cells, and SGNs (Rabio-Costa et al